J. Iran. Chem. Soc., Vol. 6, No. 2 June 2009, pp.405~411.
Current location: JICS Archive > Vol. 6 > No. 2 > Articles : 22
P2O5/SiO2 as an Efficient and Recyclable Catalyst for N-Acylation of Sulfonamides under Heterogeneous and Solvent-free Conditions
A.R. Massah*, M. Dabagh, S. Shahidi, H. Javaherian Naghash, A.R. Momeni and H. Aliyan
Department of Chemistry, Islamic Azad University Shahreza Branch, Shahreza, Isfahan, I. R. Iran. P.O. Box: 86145-311
A convenient synthetic method for N-acylation of sulfonamides in the presence of P2O5/SiO2 is described. Carboxylic acid anhydrides and carboxylic acid chlorides were used as acylating agents and the reactions were carried out in CH2Cl2 or solvent-free conditions. The catalyst can be recovered by simple filtration and can be used in the subsequent reactions.
Keywords: N-Acylsulfonamide, Solvent-free, Diphosphorous pentoxide, Heterogeneous condition, N-Acylation
