1,3-Dihalo-5,5-dimethylhydantoin/NaNO₂ as an Efficient Heterogeneous System for the N-Nitrosation of N,N-Dialkylamines under Mild Conditions

K. Niknam^a,* and M.A. Zolfigol^b

^aChemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr, 75168, Iran

^bChemistry Department, College of Science, Bu-Ali Sina University, Hamadan, 65174, Iran

 (Received 1 October 2005, Accepted 26 December 2005)

     A combination of 1,3-dihalo-5,5-dimethylhydantoin (X = Br, Cl) and sodium nitrite in the presence of wet SiO₂  was used as an effective nitrosating agent for the nitrosation of N,N-dialkyl amines to their corresponding nitroso derivatives under mild and heterogeneous conditions in good to excellent yields.

Keywords: 1,3-Dihalo-5,5-dimethylhydantoin, Nitrosation, N,N-dialkyl amines, N-nitrosoamines, Sodium nitrite