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Article info. : 2005; 2(4) (pp 244~337)


Synthesis of Triphenylmethylphosphonium Chlorochoromate as A Mild and Selective Reagent for Oxidation of Alcohols

A.R. Hajipoura,b,*, L. Khazdooza and A.E. Ruohob

aPharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
bDepartment of Pharmacology, University of Wisconsin Med. Sch. 1300 University Avenue, Madison, 53706-1532, WI, USA

(Received 4 September2005, Accepted 1November 2005)

Triphenylmethylphosphonium chlorochoromate was synthesized from triphenylmethyl bromide and chromium(VI) oxide in HCl 6 N and used as an efficient and selective reagent for oxidation of alcohols to their corresponding aldehydes or ketones derivatives in refluxing acetonitrile in good to excellent yields.

Keywords: Alcohols, Aldehydes, Ketones, Oxidation, Triphenylmethylphosphonium chlorochoromate


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