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Article info. : 2005; 2(2) (pp 115~123)


Pyrazoles as Building Blocks in Heterocyclic Synthesis: Synthesis of Pyrazolo [3,4-d]pyrimidine, Pyrazolo[3,4-e][1,4]diazepine, Pyrazolo [3,4-d][1,2,3]triazine and Pyrolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Derivatives

A.-F.A. Harb*, H.H. Abbas and F.H. Mostafa
Chemistry Department, Faculty of Science (Qena), South Valley University,Qena, 83523, Egypt.

Several new pyrazolo[3,4-d]pyrimidine, pyrazolo[3,4-e][1,4]diazepine, pyrazolo[3,4-d][1,2,3]triazine and pyrolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives were prepared by the reaction of the corresponding 5-amino-pyrazole-4-carbonitrile derivative with different organic reagents under different reaction conditions. Using IR, 1H NMR, and mass spectra we have characterized all new compounds.

Keywords: Pyrazolo[3,4-d]pyrimidine, Pyrazolo[3,4-e][1,4]diazepine, Pyrazolo[3,4-d][1,2,3]-triazine, Pyrolo[4,3-e][1,2,4] diazole[1,5-a]pyrimidine, IR, 1H NMR


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