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Synthesis of Quinolines Using Nano-Flake ZnO as a New Catalyst under Solvent-Free Conditions

M. Hosseini-Sarvari^a,*

^aDepartment of Chemistry, College of Science, Shiraz University, Shiraz, 71454, Iran

     Catalytic activity of nano-flake ZnO for synthesis of quinoline derivatives and their related polyheterocycles under solvent-free conditions has been studied. Nano-flake ZnO has been successfully synthesized by conventional heating of a solution approach using ZnOAc.2H₂O and Urea. This method is simple, cost-effective, and environmentally benign and the catalyst can be reused for several times. 

Keywords: Quinoline, Nano ZnO, Friedlander reaction, Solvent-free