J. Iran. Chem. Soc., Vol. 8, No. 2 June 2011, pp.545~552.

Current location: JICS Archive > Vol. 8 > No. 2 > Articles : 20

A Simple Green Approach to the Synthesis of 2-Amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile Derivatives Catalyzed by 3-Hydroxypropanaminium Acetate (HPAA) as a New Ionic Liquid

H.R. Shaterian* and A.R. Oveisi

Department of Chemistry, Faculty of Sciences, the University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran

     A new ionic liquid, 3-hydroxypropanaminium acetate (HPAA) [H3N+-CH2-CH2-CH2-OH][CH3COO-], was synthesized for the first time and used as an efficient and recoverable catalyst in the synthesis of 2-amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives by condensing together 4-hydroxycoumarin, aldehydes and malononitrile at room temperature. The catalyst can be reused for four times without noticeable loss of activity.

Keywords: 2-Amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile, Ionic liquid, Multi-component reaction, Catalysis

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