J. Iran. Chem. Soc., Vol. 7, No. 4 December 2010, pp.859~863.

Current location: JICS Archive > Vol. 7 > No. 4 > Articles : 10

An Efficient Approach for the Synthesis of N-Phenylcarboxamido-2-aryl-1,2-dihydro-(4H)-3,1-benzoxazine-4-ones  

S. Irani and F. Nikpour*

Department of Chemistry, Faculty of Sciences, The University of Kurdistan, P.O. Box 66315-416, Sanandaj, Iran

An efficient synthesis of N-phenylcarboxamodo-2-aryl-1,2-dihydro-(4H)-3,1-benzoxazin-4-ones is described by cyclization reaction of some 2-(benzylidene-amino)-benzoic acids with phenyl isocyanate under reflux conditions in CHCl3. Higher yields of the products were produced  in high purity with simple work-up.

Keywords: 1,2-Dihydro-3,1-benzoxazin-4-ones, Anthranilic acid, Phenyl isocyanate, Schiff base, Cyclization reaction

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