J. Iran. Chem. Soc., Vol. 7, No. 3 September 2010, pp.615~620.

Current location: JICS Archive > Vol. 7 > No. 3 > Articles : 8

H14[NaP5W30O110] Catalyzed One-Pot Three-Component Synthesis of Dihydropyrano[2,3-c]pyrazole and pyrano[2,3-d]pyrimidine Derivatives

M.M. Heravia,*, A. Ghodsa, F. Derikvanda,*, K. Bakhtiaria and F.F. Bamoharramb

aDepartment of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
bDepartment of Chemistry, Islamic Azad University-Mashhad Branch, Mashhad, Iran

This is a report of an efficient, clean and facile method for the synthesis of 1,4-dihydropyrano[2,3-c] pyrazole and pyrano[2,3-d]pyrimidine derivatives via three-component one-pot condensation of 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one or barbituric acid, aldehydes and malononitrile in the presence of a catalytic amount of preyssler type heteropolyacid as a green and reusable catalyst in water or ethanol under refluxing conditions.

Keywords: 1,4-Dihydropyrano[2,3-c]pyrazoles, Pyrano[2,3-d]pyrimidines, On water reactions, Preyssler type heteropoly acid, Multi-component reactions

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