A High Yielding, One-Pot Synthesis of S,S-Dialkyl Dithiocarbonates Through the Corresponding Thiols Using Mitsunobu’s Reagent

A.K. Chaturvedi^a,D. Chaturvedi^b,, N. Mishra^a and V. Mishra^a*

^aSynthetic Research Laboratory, Department of Chemistry, B. S. A. P. G. College, Mathura-281004, U. P., India
^bBio-Organic Chemistry Division, Indian Institute of Integrative Medicine, Canal Road, Jammu-Tawi-180001, J. & K., India

A novel Mitsunobu-based technique has been developed for the synthesis of a variety of symmetrical and unsymmetrical S,S-dialkyl dithiocarbonates from various corresponding primary, secondary and tertiary thiols using gaseous carbon dioxide, in good to excellent yields.

Keywords: Synthesis, Dialkyl dithiocarbonates, Thiols, Carbon dioxide, Mitsunobu’s reagent

A High Yielding, One-Pot Synthesis of S,S-Dialkyl Dithiocarbonates Through the Corresponding Thiols Using Mitsunobu’s Reagent

A.K. Chaturvedia, D. Chaturvedib,*, N. Mishraa and V. Mishraa

aSynthetic Research Laboratory, Department of Chemistry, B. S. A. P. G. College, Mathura-281004, U. P., India bBio-Organic Chemistry Division, Indian Institute of Integrative Medicine, Canal Road, Jammu-Tawi-180001, J. & K., India

A.K. Chaturvedi^a,D. Chaturvedi^b,, N. Mishra^a and V. Mishra^a*

^aSynthetic Research Laboratory, Department of Chemistry, B. S. A. P. G. College, Mathura-281004, U. P., India
^bBio-Organic Chemistry Division, Indian Institute of Integrative Medicine, Canal Road, Jammu-Tawi-180001, J. & K., India