J. Iran. Chem. Soc., Vol. 7, No. 1 March 2010, pp.227~236.

Current location: JICS Archive > Vol. 7 > No. 1 > Articles : 27

Molecular Iodine: An Efficient Catalyst for the One-Pot Synthesis of Primary 1-Aminophosphonates

S. Sobhani* and A. Vafaee

Department of Chemistry, College of Sciences, Birjand University, Birjand 414, Iran

A new and convenient procedure has been developed for the one-pot synthesis of different types of primary 1-aminophosphonates from aldehydes/ketones, HMDS and diethyl phosphite using I2 as an inexpensive, non-toxic, non-metallic and readily available catalyst. These reactions proceeded under solvent-free conditions and produced the desired products in high yields.

Keywords: 1-Aminophosphonates, Aldehydes, Ketones, Diethyl Phosphite, Iodine

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