J. Iran. Chem. Soc., Vol. 7, No. 1 March 2010, pp.114~118.

Current location: JICS Archive > Vol. 7 > No. 1 > Articles : 11

A Rapid and Convenient Method for the Synthesis of Aldoximes under Microwave Irradiation Using in situ Generated Ionic Liquids

A.R. Hajipoura, b,*, F. Rafieea and A.E. Ruohob

aPharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
bDepartment of Pharmacology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI, USA 53706-1532

We have developed a chemoselective, simple and efficient method for the preparation of aldoximes using microwave irradiation in the presence of tribenzylamine or 1,4-diazabicyclo[2.2.2]octane or 1-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide as bases and useful precursors for in situ generation of ionic liquids.

Keywords: Oxime, Hydroxylamine hydrochloride, Ionic liquid, Microwave irradiation

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