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J. Iran. Chem. Soc., Vol. 5, Supp. 1 October 2008, pp.S91~S96.

Current location: JICS Archive > Vol. 5 > Supplement. 1 > Articles : 12

The First Report on the Synthesis of New Hantzsch N-Ethyldimetyl Acetal-1,4-dihydropyridines with Aldehyde Synthon under Microwave Irradiation


M.A. Zolfigol* and M. Mokhlesi


Faculty of Chemistry, Bu-Ali Sina University, Hamedan, Iran


A mixture of ethyl acethylenecarboxylate, various aryl aldehydes and aminoacetaldehyde dimethyl acetal in the presence of silica gel were converted to N-ethyldimethyl acetal-1,4-dihydropyridines using microwave irradiation with good yields.


Keywords: N-ethyldimethyl acetal-1, 4-Dihydropyridines 1,4-Dihydropyridines, Aminoacetaldehyde dimethyl acetal, Ethyl acethylenecarboxylate, Solvent-free, Microwave irradiation.

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