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J. Iran. Chem. Soc., Vol. 4, No. 4 December 2007, pp.497~502.

Current location: JICS Archive > Vol. 4 > No. 4 > Articles : 15

Synthesis a Novel Class of Unsaturated Cyclic Compounds Containing Phosphorus Atom Using Pseudo Four-Component Condensation Reactions


A. Shaabani* and E. Soleimani


Department of Chemistry, Shahid Beheshti University, P.O. Box 19396-4716, Tehran, Iran


A novel pseudo four-component condensation reaction for the efficient synthesis of 2λ5-[1,2]oxaphosphinin compounds using triphenylphosphine and ethyl bromoacetate in the presence of electron-deficient acetylenic esters without using any catalyst and activation is reported. Fully functionalized 2λ5-[1,2]oxaphosphinin derivatives can be prepared from simple and readily available precursors under neutral conditions.


Keywords: Ethyl bromoacetate, 2λ5-[1,2]Oxaphosphinin, Acetylenic ester, Multi-component reactions

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