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J. Iran. Chem. Soc., Vol. 3, No. 3 September 2006, pp.220~222.

Current location: JICS Archive > Vol. 3 > No. 3 > Reviews : 2

Advantages of USP Apparatus IV (Flow-through Cell Apparatus) in Dissolution Studies


I. Singha and H.Y. Aboul-Eneinb,*


aAkal College of Pharmacy and Technical Education, Mastuana Sahib, Sangrur-148001, Punjab, India
bMedicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division,
National Research Centre, Tahrir St., Dokki-Cairo, 12311, Egypt.


The basic characteristics of the flow-through cell apparatus (USP Apparatus IV) including the assembly and open/closed configuration of the apparatus have been described. The relative advantages of the flow-through cell apparatus over other release setups have been summarized. Finally, potential applications of this setup are presented.


Keywords: Flow-through cell apparatus, USP apparatus IV, Drug dissolution

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