J. Iran. Chem. Soc., Vol. 3, No. 1 March 2006, pp.93~97.
Current location: JICS Archive > Vol. 3 > No. 1 > Articles : 13
Environmentally Friendly Room Temperature Strecker Reaction: One-Pot Synthesis of α-Aminonitriles in Ionic Liquid
M.M. Mojtahedi*, M.S. Abaee and H. Abbasi
Chemistry & Chemical Engineering Research Center of Iran, P.O.Box 14335-186, Tehran, Iran
A three component efficient and facile procedure is developed for the synthesis of α-aminonitriles from aromatic and aliphatic aldehydes, amines, and trimethylsilyl cyanide in 1-butyl-3-methyl-1H-imidazolium perchlorate ([bmim][ClO4]) ionic liquid as the reaction medium at room temperature. Excellent yields are obtained in this one-pot procedure with short reaction times and the ionic liquid medium reused several times in a row.
Keywords: Ionic liquids, Strecker reaction, α-Aminonitriles, Imminium ions
