Synthesis of Triphenylmethylphosphonium Chlorochoromate as A Mild and Selective Reagent for Oxidation of Alcohols

A.R. Hajipour^a,b,, L. Khazdooz^a and A.E. Ruoho^b*

^aPharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
^bDepartment of Pharmacology, University of Wisconsin Med. Sch. 1300 University Avenue, Madison, 53706-1532, WI, USA

Triphenylmethylphosphonium chlorochoromate was synthesized from triphenylmethyl bromide and chromium(VI) oxide in HCl 6 N and used as an efficient and selective reagent for oxidation of alcohols to their corresponding aldehydes or ketones derivatives in refluxing acetonitrile in good to excellent yields.

Keywords: Alcohols, Aldehydes, Ketones, Oxidation, Triphenylmethylphosphonium chlorochoromate

Synthesis of Triphenylmethylphosphonium Chlorochoromate as A Mild and Selective Reagent for Oxidation of Alcohols

A.R. Hajipoura,b,*, L. Khazdooza and A.E. Ruohob

aPharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, IranbDepartment of Pharmacology, University of Wisconsin Med. Sch. 1300 University Avenue, Madison, 53706-1532, WI, USA

A.R. Hajipour^a,b,, L. Khazdooz^a and A.E. Ruoho^b*

^aPharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
^bDepartment of Pharmacology, University of Wisconsin Med. Sch. 1300 University Avenue, Madison, 53706-1532, WI, USA